Systems Biology in Reproductive Medicine 2019

Systems biology, toxins, obesity, and functional medicine.

By recognizing the role of toxins in obesity and altered function of the neuro-endocrine-immune and mitochondrial and redox systems, and by creating a comprehensive strategy for both the reduction of exposure to and elimination of toxins, as well as the development of effective clinical strategies, treatment resistance in obesity may be more successfully addressed. Further research is needed to...

Personalizing medicine: a systems biology perspective

Systems biology and the future of medicine.

Contemporary views of human disease are based on simple correlation between clinical syndromes and pathological analysis dating from the late 19th century. Although this approach to disease diagnosis, prognosis, and treatment has served the medical establishment and society well for many years, it has serious shortcomings for the modern era of the genomic medicine that stem from its reliance on...

Systems biology: personalized medicine for the future?

Systems biology is actively transforming the field of modern health care from symptom-based disease diagnosis and treatment to precision medicine in which patients are treated based on their individual characteristics. Development of high-throughput technologies such as high-throughout sequencing and mass spectrometry has enabled scientists and clinicians to examine genomes, transcriptomes, pro...

Personalizing medicine: a systems biology perspective

According to the SEER Cancer Statistics Review, between 1975 and 2005, the deaths from heart disease in the United States declined from 37.8 to 26.6%, whereas over the same period those from cancer increased from 19.2 to 22.8% (Ries et al, 2008). In the US alone, it is estimated that in 2008 a total of 565,650 patients will have died from cancer, whereas 1,437,180 will have been newly diagnosed...